Based on these favorable findings, the researchers concluded that tocotrienols may have potential for metabolic syndrome therapy especially on cardiovascular and liver health, and therefore is worth further investigation.
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Over the past eight years, the International Conference on Palm Phytonutrients and Chronic Diseases has provided a good platform for researchers and the industry to share the latest research and findings on palm phytonutrients with research scientists, medical doctors and formulators.
Researchers at Ohio State University Wexner Medical Center uncovered a novel pathway for hair follicular regeneration. Palm tocotrienol complex (EVNol SupraBio) was shown to induce hair follicle growth via protein expression of epidermal E-cadherin dependent beta-catenin, the key signaling molecule for inducing pluripotent stem cells in the adult skin.
Malaysian red palm oil is a rich natural source of alpha- and beta-carotene.
For decades, international food manufacturers have associated Malaysian-sourced palm oil with quality. This proud nation produces more than 40 percent of the world’s certified sustainable palm oil. The United States, as well as other countries with high standards, imports most of its palm oil from Malaysia because the country is dedicated to palm oil quality.
Apart from ingesting carotenoid-rich foods, a convenient way of attaining high levels of alpha-carotene and beta-carotene is via dietary supplements.
The new study demonstrates that oral administration of high dose of alpha-tocopherol as well as mixed-tocotrienol do not cause any significant negative effects on bone mass, bone microarchitecture, bone formation and bone marrow osteogenic (bone forming) gene expressions.
Long-term supplementation of mixed-carotene may help to regulate metabolic health in obese children.
The results from this study, collectively, show that both alpha-carotene and gamma-tocopherol may help in the modulation of metabolic-inflammatory processes.
When comparing to the control group, the tocotrienols-treated mice demonstrated reduced tumor sizes and tumor volumes in a dose-dependent manner.