This post was originally published on October 3, 2016 and updated on October 7, 2020.

A recent clinical study may have adults with metabolic syndrome racing to supplement with full-spectrum tocotrienols. The results from this human clinical study show a link between consumption of the palm oil-derived tocotrienols and a reduction of LDL cholesterol, diastolic blood pressure and certain inflammatory markers. The tocotrienol supplement used in the study was EVNol SupraBio, which is produced from pure Malaysian certified sustainable palm oil.

Metabolic syndrome is characterized by several conditions including increased blood pressure, high blood sugar, abnormal cholesterol levels and a tendency to store excess fat around the waist. Those with metabolic syndrome have an increased risk of heart disease, stroke and diabetes.

In this study, 70 adults with metabolic syndrome (aged 20 – 60 year-old) were randomized to receive either palm mixed tocotrienols (EVNol SupraBio) or a placebo for 16 weeks. Participants underwent evaluation of body composition, anthropometric data, dietary intake, physical activeness and blood pressure prior to supplementation and again at 8 and 16 weeks. Blood cholesterol levels and inflammatory markers were also measured at baseline and at week 16.

Participants who received palm tocotrienols showed several health benefits:

  • A significant reduction in inflammatory markers, such as Interlukin-6 (IL-6) (13.9 percent) and tumor necrosis factor-alpha (TNF-α )(10.6 percent)
  • Reduction in diastolic blood pressure (5.4 percent)
  • Decrease of total serum cholesterol levels (4.6 percent)
  • Decrease of LDL cholesterol levels (5.3 percent)

ExcelVite Sdn. Bhd nutritionist CheeYen Lau commented on the study: “Metabolic syndrome is a cluster of risk factors, and we are thrilled to know that subjects supplemented with EVNol SupraBio maintained a healthy range of cholesterol and blood pressure. To date, this is the first study to show that supplementation with tocotrienol attenuates the production of inflammatory markers such as IL-6 and TNF-α in metabolic syndrome subjects. Both IL-6 and TNF-α are strongly associated with obesity-induced inflammatory process, which constitutes the main contributing factor to metabolic syndrome.”

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Malaysian palm oil is a rich source of tocotrienols, which are part of the vitamin E complex. While extremely beneficial, many people aren’t getting enough tocotrienols from the foods they eat. “Tocotrienols are scarce in nature. Therefore, it is highly recommended to consume food or beverages fortified with tocotrienols or dietary supplements to attain the biological effective dosage for health maintenance,” said Lau.

EVNol SupraBio is produced by ExcelVite, the only GMP-certified tocotrienol manufacturer.

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