Tocotrienols from Malaysian palm oil may inhibit your body’s fat cell production

A new study published in Food and Chemical Technology indicates that vitamin E tocotrienols derived by Malaysian palm oil may slow your body’s ability to create new fat cells and kill off some of the fat cells you already have. While this area of research in its preliminary stages, it may one day lead to tocotrienols becoming a new tool for resolving America’s obesity epidemic.

In the study, researchers from National Taiwan University evaluated the effects of four different forms of vitamin E on the ability of fat cells to multiply. Then they looked at which form of vitamin E appeared to be most effective at starting the process leading to fat cell death. The forms evaluated were: alpha-tocopherol, alpha-tocotrienol, gamma-tocotrienol and delta-tocotrienol. The oil palm is nature’s most abundant plant source of tocotrienols.

The results showed that gamma-tocotrienol appeared to both inhibited the proliferation of fat cells and induced or triggered fat cell death. In their report, the authors described various methods for how this happens in the body.

“Obesity has become an epidemic especially in the U.S. It is well recognized that obesity is linked to metabolic syndrome and other serious medical conditions in adults (such as type 2 diabetes, cardiovascular diseases and liver disease) that would lead to an increase in disability adjusted life years. Therefore, increasing effort is made by researchers all over the world to find solutions to address obesity. A rat study published in 2004 reported body fat mass reduction after 8 weeks of gamma-tocotrienol supplementation,” says WH Leong, vice president of Carotech Inc.

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“This particular study further shows that gamma-tocotrienol is the most effective form of vitamin E in reducing fat cell numbers via regulating specific signaling pathways. Tocomin palm tocotrienol complex contains a very high level of gamma-tocotrienol, which underscores the benefit of using it as a natural supplement in managing obesity,” adds Leong.

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